Upping Brightness 1000-Fold

1000-fold sample focusing on paper-based microfluidic devices.

We present an experimental and analytical study of a novel paper-based analytical device (μPAD) for isotachophoretic sample focusing. Guided by a simple heat transfer model, we further developed wax printing fabrication to enable the creation of shallow channels, which are critical in providing sufficient dissipation of Joule heat, and thus enable the use of high electric fields and short analy...

Revealing stellar brightness profiles by means of microlensing fold caustics

With a handful of measurements of limb-darkening coefficients, galactic microlensing has already proven to be a powerful technique for studying atmospheres of distant stars. Survey campaigns such as OGLE-III are capable of providing ∼ 10 suitable target stars per year that undergo microlensing events involving passages over the caustic created by a binary lens, which last from a few hours to a ...

Upping the Ante

One-upping the LD50.

Proliferative lesions in the livers of mice treated 18 months previously with cisplatin Sir-Cis-diammine-dichloroplatinum II ('cisplatin') is a widely used cytotoxic agent that is known to cause long-term renal insufficiency. Bulger and Dobyan (1984) and Dobyan (1985) have reported hyperplastic lesions in the kidneys of rats treated 6 and 15 months previously with a single intraperitoneal dose ...

1000-fold enhancement in proton conductivity of a MOF using post-synthetically anchored proton transporters

Pyridinol, a coordinating zwitter-ionic species serves as stoichiometrically loadable and non-leachable proton carrier. The partial replacement of the pyridinol by stronger hydrogen bonding, coordinating guest, ethylene glycol (EG), offers 1000-fold enhancement in conductivity (10(-6) to 10(-3) Scm(-1)) with record low activation energy (0.11 eV). Atomic modeling coupled with (13)C-SSNMR provid...